ROLE OF CAPN-10, TCF7L2, PPARG AND KCNJ11 GENE IN TYPE 2 DIABETES MELLITUS (T2DM)
نویسندگان
چکیده
منابع مشابه
Investigation of polymorphisms rs7903146 and rs12255372 in the TCF7L2 gene in biochemical markers of severity of type 2 diabetes mellitus (T2DM) in a sample of adults with T2DM
Investigation of polymorphisms rs7903146 and rs12255372 in the TCF7L2 gene in biochemical markers of severity of type 2 diabetes mellitus (T2DM) in a sample of adults with T2DM Simone Morelo Dal Bosco, Cristiane dos santos Costa, Adriana Regina Bitello, Crislene Sippel, Rafaela Bastian, Maria Wollinger, Julio Dessoy, Olívia Bouchacourt, Rosangela Leipinitz, Veronica Contini, Claudete Rempel, Ju...
متن کاملType 2 diabetes mellitus (T2DM) and hepatitis C virus
Background:A high prevalence of hepatitis C virus (HCV) infection in patients with diabetic kidney disease (DKD) has been reported. However, the epidemiology and relationship between DKD and occult HCV infection (OCI)are unknown.Objetives: To determine the prevalence of OCI in a population without conventional markers of HCV infection diagnosed with DKD, and to study its possible clinical impli...
متن کاملImpact of Common Variants of PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 on the Risk of Type 2 Diabetes in 5,164 Indians
OBJECTIVE Common variants in PPARG, KCNJ11, TCF7L2, SLC30A8, HHEX, CDKN2A, IGF2BP2, and CDKAL1 genes have been shown to be associated with type 2 diabetes in European populations by genome-wide association studies. We have studied the association of common variants in these eight genes with type 2 diabetes and related traits in Indians by combining the data from two independent case-control stu...
متن کاملAssociation of rs12255372 in the TCF7L2 gene with type 2 diabetes mellitus: a meta-analysis
Our objective was to evaluate the association of rs12255372 in the TCF7L2 gene with type 2 diabetes mellitus (T2DM) in the world population. We carried out a survey of the literature about the effect of rs12255372 on genetic susceptibility to T2DM by consulting PubMed, the Cochrane Library, and Embase from 2006 to 2012, and then performed a meta-analysis of all the studies in order to evaluate ...
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Background: Type 2 diabetes mellitus (T2DM) is the most common type of diabetes that was classically characterized by pancreatic β-cell dysfunction. Changes in circadian patterns is one of the reasons which can increase the occurrence of diabetes. Melatonin is one of the biological molecules which plays an important role in regulating the circadian clock and also an inhibitory effect on insulin...
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ژورنال
عنوان ژورنال: Era's Journal of Medical Research
سال: 2018
ISSN: 2348-9839,2394-5222
DOI: 10.24041/ejmr2018.86